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AI in medicine falls into three interaction levels—assisted, augmented and automated—each producing distinct effects on work, productivity and management. Rather than simply displacing clinicians, the dominant trajectory is toward Human+ professionals who supervise, exercise higher-order judgment and manage exceptions.

Toward human+ medical professionals: navigating AI integration in healthcare to enhance human expertise
Claudia Perillo, Domenica Lavorato, Manuel Villasalero · March 08, 2026 · European Journal of Innovation Management
openalex descriptive low evidence 7/10 relevance DOI Source PDF
Using four healthcare case studies, the paper proposes a three-level taxonomy—AI-assisted, AI-augmented, AI-automated—that maps to different innovation effects and predicts a shift toward 'Human+' roles (complementarity) rather than wholesale clinician replacement.

Purpose This study aims to analyse the different levels of human–AI interaction in healthcare and their impact on human expertise within innovation management practices. Specifically, the research seeks to investigate how the use of AI in healthcare transforms medical practitioners into Human + professionals, and what are the implications for innovation management practices. Design/methodology/approach This study employs a qualitative research design based on a multiple case study approach. Four AI applications in healthcare were selected and analysed to explore various configurations of AI–human interactions. Data analysis was guided by the three-dimensional conceptual framework proposed by Bolton et al. (2018), which provides a comprehensive lens for examining service innovation dynamics within AI-enabled healthcare systems. Findings Drawing on Bolton et al. (2018) framework, the research identifies three levels of AI interaction in healthcare, each linked to innovation categories, human expertise and impact on innovation management. Case studies illustrate varying AI integration levels: AI-assisted automates highly repetitive tasks, increasing service availability, AI-augmented supports real-time medical tasks and AI-automated streamlines processes while preserving human oversight. The analysis highlights how AI reshapes healthcare, emphasising the irreplaceable role of human expertise in innovation. Originality/value This study provides a theoretical lens for analysing and interpreting AI adoption in healthcare, highlighting the spectrum of AI roles, innovation categories and impacts. It offers a valuable framework for managing human–AI interactions while preserving human expertise in the evolutionary path toward Human+.

Summary

Main Finding

The study identifies a three-level taxonomy of human–AI interaction in healthcare (AI-assisted, AI-augmented, AI-automated) that maps to distinct innovation categories, different impacts on human expertise, and divergent implications for innovation management. Across four case studies, AI reshapes medical work by enhancing availability, real-time decision support, or process streamlining, while human expertise remains essential — producing a trajectory toward “Human+” professionals rather than wholesale replacement.

Key Points

  • Purpose: To analyze how different forms of AI use in healthcare transform practitioners into Human+ professionals and affect innovation management practices.
  • Conceptual frame: Analysis uses Bolton et al. (2018)’s three-dimensional service-innovation framework to interpret service, technology, and organizational dynamics.
  • Empirical approach: Multiple qualitative case studies of four AI healthcare applications, chosen to illustrate different AI–human configurations.
  • Three interaction levels:
    • AI-assisted — automates highly repetitive tasks (e.g., triage routing, routine image preprocessing). Primary innovation effect: increased service availability and throughput; impact: frees clinician time but requires oversight and integration into workflows.
    • AI-augmented — supports real-time medical tasks (e.g., decision support during procedures). Primary innovation effect: amplifies human judgment and speed; impact: raises required cognitive skills, changes training needs and coordination practices.
    • AI-automated — streamlines end-to-end processes while keeping humans in supervisory/exception roles (e.g., automated reporting pipelines with human sign-off). Primary innovation effect: process reconfiguration and efficiency gains; impact: shifts roles toward exception management and governance.
  • Core insight: Adoption is better framed as evolution to Human+ capabilities (complementarity) rather than simple substitution; innovation management must preserve and cultivate human expertise even as tasks move to AI.
  • Limitations: Qualitative, small-sample case approach—interpretive and illustrative rather than statistically generalizable.

Data & Methods

  • Design: Qualitative multiple case study.
  • Sample: Four AI applications in healthcare selected to represent different configurations of AI–human interaction (details not specified in the abstract).
  • Analytical framework: Bolton et al. (2018) three-dimensional framework for service innovation, used to map technological configuration, service processes, and organizational/skill implications.
  • Analysis: Cross-case comparison to derive levels of interaction, link them to innovation categories, and infer impacts on human expertise and innovation management.
  • Methodological notes: Exploratory interpretive analysis appropriate for theory-building; suggests need for subsequent quantitative validation (productivity, labor-market effects, outcomes).

Implications for AI Economics

  • Task structure and labor demand
    • The taxonomy clarifies where substitution vs. complementarity are likely: AI-assisted tasks imply partial substitution of routine work; AI-augmented applications generate complementarities that increase demand for higher cognitive skills; AI-automated systems can shift labor toward monitoring, exception handling, and governance.
    • Predicts compositional shifts in health labor markets (downward demand for some routine roles, upward demand/returns for clinical judgment, coordination and data-literacy skills).
  • Productivity and value creation
    • Different interaction levels produce heterogenous productivity gains (throughput increases, faster/safer decisions, process cost reductions). Economic evaluation should be level-specific.
    • Value capture and pricing models will differ (e.g., per-use service expansions for AI-assisted; outcome- or decision-value pricing for AI-augmented; platform/process contracting for AI-automated systems).
  • Innovation management and firm strategy
    • Firms and hospitals need differentiated investment and governance strategies by interaction level: emphasis on integration and workflow redesign for AI-assisted; training and decision-support protocols for AI-augmented; process redesign, liability allocation, and oversight systems for AI-automated.
    • R&D and procurement choices should account for complementarities with human capital and the costs of retraining and governance.
  • Policy and regulation
    • Regulation should be calibrated to interaction level: stronger oversight and validation for AI-augmented/automated systems that affect clinical decisions; workforce policies (reskilling subsidies, credentialing) to manage transitions toward Human+ roles.
    • Payment systems and incentives (reimbursement, procurement) need to internalize long-run returns to complementary human skills and system-level gains.
  • Measurement and research agenda
    • Calls for quantitative follow-ups to estimate causal impacts on productivity, health outcomes, wages, and employment composition across the three interaction levels.
    • Suggests using task-based, matched employer-employee, and provider-level panel data to measure complementarities and redistribution effects.
    • Recommends economic models that incorporate service innovation dynamics (adoption externalities, learning-by-doing, regulation) and heterogenous returns by AI–human configuration.

Overall, the paper provides a practical taxonomy that can help economists and policymakers predict where AI will augment vs. displace healthcare work, prioritize measurement efforts, and design targeted interventions (training, procurement, regulation) to capture productivity gains while preserving essential human expertise.

Assessment

Paper Typedescriptive Evidence Strengthlow — Findings are drawn from four qualitative, illustrative case studies without counterfactuals, statistical analysis, or causal identification; useful for theory-building but not for estimating magnitudes or causal impacts on productivity, wages, or employment. Methods Rigormedium — Appropriate and transparent interpretive methods for exploratory theory-building (use of an established service-innovation framework and cross-case comparison), but limited by a small, non-random case sample, unspecified selection criteria and data sources, and absence of systematic triangulation or robustness checks. SampleFour qualitative case studies of AI applications in healthcare chosen to exemplify different human–AI configurations (examples referenced include triage routing and preprocessing, real-time decision support during procedures, and automated reporting pipelines with human sign-off); specific sites, sample sizes, respondent details, and data collection procedures are not reported in the abstract. Themeshuman_ai_collab productivity labor_markets skills_training org_design governance innovation GeneralizabilitySmall, non-random case sample limits external validity, Sector-specific (healthcare) — patterns may not hold in other industries, Likely variation across health systems, countries, and regulatory environments, Technology heterogeneity: findings depend on particular AI architectures and maturity, Interpretive, qualitative evidence cannot quantify economic magnitude or direction of labor market effects

Claims (12)

ClaimDirectionConfidenceOutcomeDetails
The study identifies a three-level taxonomy of human–AI interaction in healthcare: AI-assisted, AI-augmented, and AI-automated. Other null_result high classification of AI–human interaction (taxonomic mapping)
n=4
0.09
AI-assisted applications automate highly repetitive tasks (e.g., triage routing, routine image preprocessing), producing increased service availability and throughput while freeing clinician time but requiring oversight and workflow integration. Organizational Efficiency positive medium service availability, throughput, clinician time use, need for oversight/integration
n=4
0.05
AI-augmented systems support real-time medical tasks (e.g., decision support during procedures), amplifying human judgment and speed but raising required cognitive skills and changing training and coordination practices. Decision Quality mixed medium decision speed/judgment, cognitive skill requirements, training needs, coordination practices
n=4
0.05
AI-automated solutions streamline end-to-end processes (e.g., automated reporting pipelines) while keeping humans in supervisory/exception roles, producing process reconfiguration and efficiency gains and shifting roles toward exception management and governance. Task Allocation positive medium process efficiency, role composition (supervisory/exception handling), process reconfiguration
n=4
0.05
Adoption of healthcare AI is better framed as an evolution toward 'Human+' professionals (complementarity) rather than wholesale replacement of clinicians. Job Displacement positive medium degree of complementarity vs. substitution; preservation/enhancement of human expertise
n=4
0.05
The taxonomy clarifies where substitution versus complementarity are likely: AI-assisted tasks imply partial substitution of routine work; AI-augmented applications generate complementarities that increase demand for higher cognitive skills; AI-automated systems shift labor toward monitoring, exception handling, and governance. Employment mixed medium labor demand by task type (routine vs. cognitive), role shifts toward monitoring/governance
n=4
0.05
Different interaction levels produce heterogeneous productivity gains (throughput increases, faster/safer decisions, process cost reductions); economic evaluation should be level-specific. Firm Productivity positive medium productivity metrics (throughput, decision speed/safety), cost reductions
n=4
0.05
The taxonomy predicts compositional shifts in health labor markets: reduced demand for some routine roles and increased demand/returns for clinical judgment, coordination, and data-literacy skills. Employment mixed low employment composition (occupation-level demand), wage/returns for higher-skill roles
n=4
0.03
Firms and hospitals need differentiated investment and governance strategies by interaction level: integration and workflow redesign for AI-assisted; training and decision-support protocols for AI-augmented; process redesign, liability allocation, and oversight for AI-automated systems. Organizational Efficiency positive medium organizational practices (investment decisions, governance, training), implementation effectiveness
n=4
0.05
Regulation and workforce policy should be calibrated to interaction level: stronger oversight and validation for AI-augmented/automated systems and workforce policies (reskilling, credentialing) to manage transition to Human+ roles. Governance And Regulation positive low regulatory stringency by system type, workforce reskilling/credentialing uptake
n=4
0.03
The study is qualitative and small-sample (four case) and therefore interpretive and illustrative rather than statistically generalizable. Other null_result high generalizability/external validity
n=4
0.09
The paper calls for subsequent quantitative validation (using task-based, matched employer-employee, and provider-level panel data) to estimate causal impacts on productivity, health outcomes, wages, and employment composition across the three interaction levels. Research Productivity null_result high need for causal estimates of productivity, health outcomes, wages, employment composition
0.09

Notes